The Personal Human Oral Microbiome Obscures the Effects of Treatment on Periodontal Disease
Identifieur interne : 000342 ( Main/Exploration ); précédent : 000341; suivant : 000343The Personal Human Oral Microbiome Obscures the Effects of Treatment on Periodontal Disease
Auteurs : Karen Schwarzberg [États-Unis] ; Rosalin Le [États-Unis] ; Balambal Bharti [États-Unis] ; Suzanne Lindsay [États-Unis] ; Giorgio Casaburi [Italie] ; Francesco Salvatore [Italie] ; Mohamed H. Saber [États-Unis] ; Faisal Alonaizan [États-Unis] ; J Rgen Slots [États-Unis] ; Roberta A. Gottlieb [États-Unis] ; J. Gregory Caporaso [États-Unis] ; Scott T. Kelley [États-Unis]Source :
- PLoS ONE [ 1932-6203 ] ; 2014.
Abstract
Periodontitis is a progressive disease of the periodontium with a complex, polymicrobial etiology. Recent Next-Generation Sequencing (NGS) studies of the microbial diversity associated with periodontitis have revealed strong, community-level differences in bacterial assemblages associated with healthy or diseased periodontal sites. In this study, we used NGS approaches to characterize changes in periodontal pocket bacterial diversity after standard periodontal treatment. Despite consistent changes in the abundance of certain taxa in individuals whose condition improved with treatment, post-treatment samples retained the highest similarity to pre-treatment samples from the same individual. Deeper phylogenetic analysis of periodontal pathogen-containing genera
Url:
DOI: 10.1371/journal.pone.0086708
PubMed: 24489772
PubMed Central: 3906071
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000735
- to stream Pmc, to step Curation: 000735
- to stream Pmc, to step Checkpoint: 000056
- to stream Ncbi, to step Merge: 000939
- to stream Ncbi, to step Curation: 000939
- to stream Ncbi, to step Checkpoint: 000939
- to stream Main, to step Merge: 000342
- to stream Main, to step Curation: 000342
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The Personal Human Oral Microbiome Obscures the Effects of Treatment on Periodontal Disease</title><author><name sortKey="Schwarzberg, Karen" sort="Schwarzberg, Karen" uniqKey="Schwarzberg K" first="Karen" last="Schwarzberg">Karen Schwarzberg</name><affiliation wicri:level="2"><nlm:aff id="aff1"><addr-line>Department of Biology, San Diego State University, San Diego, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biology, San Diego State University, San Diego, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Le, Rosalin" sort="Le, Rosalin" uniqKey="Le R" first="Rosalin" last="Le">Rosalin Le</name><affiliation wicri:level="2"><nlm:aff id="aff1"><addr-line>Department of Biology, San Diego State University, San Diego, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biology, San Diego State University, San Diego, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Bharti, Balambal" sort="Bharti, Balambal" uniqKey="Bharti B" first="Balambal" last="Bharti">Balambal Bharti</name><affiliation wicri:level="2"><nlm:aff id="aff2"><addr-line>Graduate School of Public Health, San Diego State University, San Diego, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Graduate School of Public Health, San Diego State University, San Diego, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Lindsay, Suzanne" sort="Lindsay, Suzanne" uniqKey="Lindsay S" first="Suzanne" last="Lindsay">Suzanne Lindsay</name><affiliation wicri:level="2"><nlm:aff id="aff2"><addr-line>Graduate School of Public Health, San Diego State University, San Diego, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Graduate School of Public Health, San Diego State University, San Diego, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Casaburi, Giorgio" sort="Casaburi, Giorgio" uniqKey="Casaburi G" first="Giorgio" last="Casaburi">Giorgio Casaburi</name><affiliation wicri:level="1"><nlm:aff id="aff3"><addr-line>CEINGE-Biotecnologie Avanzate, Napoli, Italy</addr-line></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>CEINGE-Biotecnologie Avanzate, Napoli</wicri:regionArea><wicri:noRegion>Napoli</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aff4"><addr-line>Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università di Napoli Federico II, Napoli, Italy</addr-line></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università di Napoli Federico II, Napoli</wicri:regionArea><wicri:noRegion>Napoli</wicri:noRegion></affiliation></author><author><name sortKey="Salvatore, Francesco" sort="Salvatore, Francesco" uniqKey="Salvatore F" first="Francesco" last="Salvatore">Francesco Salvatore</name><affiliation wicri:level="1"><nlm:aff id="aff3"><addr-line>CEINGE-Biotecnologie Avanzate, Napoli, Italy</addr-line></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>CEINGE-Biotecnologie Avanzate, Napoli</wicri:regionArea><wicri:noRegion>Napoli</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aff4"><addr-line>Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università di Napoli Federico II, Napoli, Italy</addr-line></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università di Napoli Federico II, Napoli</wicri:regionArea><wicri:noRegion>Napoli</wicri:noRegion></affiliation></author><author><name sortKey="Saber, Mohamed H" sort="Saber, Mohamed H" uniqKey="Saber M" first="Mohamed H." last="Saber">Mohamed H. Saber</name><affiliation wicri:level="2"><nlm:aff id="aff5"><addr-line>Section of Endodontics, Herman Ostrow School of Dentistry of USC, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Section of Endodontics, Herman Ostrow School of Dentistry of USC, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Alonaizan, Faisal" sort="Alonaizan, Faisal" uniqKey="Alonaizan F" first="Faisal" last="Alonaizan">Faisal Alonaizan</name><affiliation wicri:level="2"><nlm:aff id="aff5"><addr-line>Section of Endodontics, Herman Ostrow School of Dentistry of USC, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Section of Endodontics, Herman Ostrow School of Dentistry of USC, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Slots, J Rgen" sort="Slots, J Rgen" uniqKey="Slots J" first="J Rgen" last="Slots">J Rgen Slots</name><affiliation wicri:level="2"><nlm:aff id="aff6"><addr-line>Professor of Dentistry and Microbiology, Herman Ostrow School of Dentistry of USC, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Professor of Dentistry and Microbiology, Herman Ostrow School of Dentistry of USC, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Gottlieb, Roberta A" sort="Gottlieb, Roberta A" uniqKey="Gottlieb R" first="Roberta A." last="Gottlieb">Roberta A. Gottlieb</name><affiliation wicri:level="2"><nlm:aff id="aff7"><addr-line>BioScience Center, San Diego State University, San Diego, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>BioScience Center, San Diego State University, San Diego, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Caporaso, J Gregory" sort="Caporaso, J Gregory" uniqKey="Caporaso J" first="J. Gregory" last="Caporaso">J. Gregory Caporaso</name><affiliation wicri:level="2"><nlm:aff id="aff8"><addr-line>Department of Biological Sciences, Northern Arizona University, Flagstaff, Arizona, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biological Sciences, Northern Arizona University, Flagstaff, Arizona</wicri:regionArea><placeName><region type="state">Arizona</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="aff9"><addr-line>Institute for Genomics and Systems Biology, Argonne National Laboratory, Argonne, Illinois, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Institute for Genomics and Systems Biology, Argonne National Laboratory, Argonne, Illinois</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Kelley, Scott T" sort="Kelley, Scott T" uniqKey="Kelley S" first="Scott T." last="Kelley">Scott T. Kelley</name><affiliation wicri:level="2"><nlm:aff id="aff1"><addr-line>Department of Biology, San Diego State University, San Diego, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biology, San Diego State University, San Diego, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">24489772</idno><idno type="pmc">3906071</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906071</idno><idno type="RBID">PMC:3906071</idno><idno type="doi">10.1371/journal.pone.0086708</idno><date when="2014">2014</date><idno type="wicri:Area/Pmc/Corpus">000735</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000735</idno><idno type="wicri:Area/Pmc/Curation">000735</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000735</idno><idno type="wicri:Area/Pmc/Checkpoint">000056</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000056</idno><idno type="wicri:Area/Ncbi/Merge">000939</idno><idno type="wicri:Area/Ncbi/Curation">000939</idno><idno type="wicri:Area/Ncbi/Checkpoint">000939</idno><idno type="wicri:Area/Main/Merge">000342</idno><idno type="wicri:Area/Main/Curation">000342</idno><idno type="wicri:Area/Main/Exploration">000342</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">The Personal Human Oral Microbiome Obscures the Effects of Treatment on Periodontal Disease</title><author><name sortKey="Schwarzberg, Karen" sort="Schwarzberg, Karen" uniqKey="Schwarzberg K" first="Karen" last="Schwarzberg">Karen Schwarzberg</name><affiliation wicri:level="2"><nlm:aff id="aff1"><addr-line>Department of Biology, San Diego State University, San Diego, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biology, San Diego State University, San Diego, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Le, Rosalin" sort="Le, Rosalin" uniqKey="Le R" first="Rosalin" last="Le">Rosalin Le</name><affiliation wicri:level="2"><nlm:aff id="aff1"><addr-line>Department of Biology, San Diego State University, San Diego, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biology, San Diego State University, San Diego, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Bharti, Balambal" sort="Bharti, Balambal" uniqKey="Bharti B" first="Balambal" last="Bharti">Balambal Bharti</name><affiliation wicri:level="2"><nlm:aff id="aff2"><addr-line>Graduate School of Public Health, San Diego State University, San Diego, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Graduate School of Public Health, San Diego State University, San Diego, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Lindsay, Suzanne" sort="Lindsay, Suzanne" uniqKey="Lindsay S" first="Suzanne" last="Lindsay">Suzanne Lindsay</name><affiliation wicri:level="2"><nlm:aff id="aff2"><addr-line>Graduate School of Public Health, San Diego State University, San Diego, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Graduate School of Public Health, San Diego State University, San Diego, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Casaburi, Giorgio" sort="Casaburi, Giorgio" uniqKey="Casaburi G" first="Giorgio" last="Casaburi">Giorgio Casaburi</name><affiliation wicri:level="1"><nlm:aff id="aff3"><addr-line>CEINGE-Biotecnologie Avanzate, Napoli, Italy</addr-line></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>CEINGE-Biotecnologie Avanzate, Napoli</wicri:regionArea><wicri:noRegion>Napoli</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aff4"><addr-line>Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università di Napoli Federico II, Napoli, Italy</addr-line></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università di Napoli Federico II, Napoli</wicri:regionArea><wicri:noRegion>Napoli</wicri:noRegion></affiliation></author><author><name sortKey="Salvatore, Francesco" sort="Salvatore, Francesco" uniqKey="Salvatore F" first="Francesco" last="Salvatore">Francesco Salvatore</name><affiliation wicri:level="1"><nlm:aff id="aff3"><addr-line>CEINGE-Biotecnologie Avanzate, Napoli, Italy</addr-line></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>CEINGE-Biotecnologie Avanzate, Napoli</wicri:regionArea><wicri:noRegion>Napoli</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aff4"><addr-line>Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università di Napoli Federico II, Napoli, Italy</addr-line></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università di Napoli Federico II, Napoli</wicri:regionArea><wicri:noRegion>Napoli</wicri:noRegion></affiliation></author><author><name sortKey="Saber, Mohamed H" sort="Saber, Mohamed H" uniqKey="Saber M" first="Mohamed H." last="Saber">Mohamed H. Saber</name><affiliation wicri:level="2"><nlm:aff id="aff5"><addr-line>Section of Endodontics, Herman Ostrow School of Dentistry of USC, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Section of Endodontics, Herman Ostrow School of Dentistry of USC, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Alonaizan, Faisal" sort="Alonaizan, Faisal" uniqKey="Alonaizan F" first="Faisal" last="Alonaizan">Faisal Alonaizan</name><affiliation wicri:level="2"><nlm:aff id="aff5"><addr-line>Section of Endodontics, Herman Ostrow School of Dentistry of USC, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Section of Endodontics, Herman Ostrow School of Dentistry of USC, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Slots, J Rgen" sort="Slots, J Rgen" uniqKey="Slots J" first="J Rgen" last="Slots">J Rgen Slots</name><affiliation wicri:level="2"><nlm:aff id="aff6"><addr-line>Professor of Dentistry and Microbiology, Herman Ostrow School of Dentistry of USC, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Professor of Dentistry and Microbiology, Herman Ostrow School of Dentistry of USC, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Gottlieb, Roberta A" sort="Gottlieb, Roberta A" uniqKey="Gottlieb R" first="Roberta A." last="Gottlieb">Roberta A. Gottlieb</name><affiliation wicri:level="2"><nlm:aff id="aff7"><addr-line>BioScience Center, San Diego State University, San Diego, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>BioScience Center, San Diego State University, San Diego, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Caporaso, J Gregory" sort="Caporaso, J Gregory" uniqKey="Caporaso J" first="J. Gregory" last="Caporaso">J. Gregory Caporaso</name><affiliation wicri:level="2"><nlm:aff id="aff8"><addr-line>Department of Biological Sciences, Northern Arizona University, Flagstaff, Arizona, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biological Sciences, Northern Arizona University, Flagstaff, Arizona</wicri:regionArea><placeName><region type="state">Arizona</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="aff9"><addr-line>Institute for Genomics and Systems Biology, Argonne National Laboratory, Argonne, Illinois, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Institute for Genomics and Systems Biology, Argonne National Laboratory, Argonne, Illinois</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Kelley, Scott T" sort="Kelley, Scott T" uniqKey="Kelley S" first="Scott T." last="Kelley">Scott T. Kelley</name><affiliation wicri:level="2"><nlm:aff id="aff1"><addr-line>Department of Biology, San Diego State University, San Diego, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biology, San Diego State University, San Diego, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author></analytic><series><title level="j">PLoS ONE</title><idno type="eISSN">1932-6203</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Periodontitis is a progressive disease of the periodontium with a complex, polymicrobial etiology. Recent Next-Generation Sequencing (NGS) studies of the microbial diversity associated with periodontitis have revealed strong, community-level differences in bacterial assemblages associated with healthy or diseased periodontal sites. In this study, we used NGS approaches to characterize changes in periodontal pocket bacterial diversity after standard periodontal treatment. Despite consistent changes in the abundance of certain taxa in individuals whose condition improved with treatment, post-treatment samples retained the highest similarity to pre-treatment samples from the same individual. Deeper phylogenetic analysis of periodontal pathogen-containing genera <italic>Prevotella</italic> and <italic>Fusobacterium</italic> found both unexpected diversity and differential treatment response among species. Our results highlight how understanding interpersonal variability among microbiomes is necessary for determining how polymicrobial diseases respond to treatment and disturbance.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Dentino, A" uniqKey="Dentino A">A Dentino</name></author><author><name sortKey="Lee, S" uniqKey="Lee S">S Lee</name></author><author><name sortKey="Mailhot, J" uniqKey="Mailhot J">J Mailhot</name></author><author><name sortKey="Hefti, Af" uniqKey="Hefti A">AF Hefti</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Teles, R" uniqKey="Teles R">R Teles</name></author><author><name sortKey="Teles, F" uniqKey="Teles F">F Teles</name></author><author><name sortKey="Frias Lopez, J" uniqKey="Frias Lopez J">J Frias-Lopez</name></author><author><name sortKey="Paster, B" uniqKey="Paster B">B Paster</name></author><author><name sortKey="Haffajee, A" uniqKey="Haffajee A">A Haffajee</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Genco, Rj" uniqKey="Genco R">RJ Genco</name></author><author><name sortKey="Borgnakke, Ws" uniqKey="Borgnakke W">WS Borgnakke</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cullinan, Mp" uniqKey="Cullinan M">MP Cullinan</name></author><author><name sortKey="Seymour, Gj" uniqKey="Seymour G">GJ Seymour</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Slots, J" uniqKey="Slots J">J Slots</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Liu, B" uniqKey="Liu B">B Liu</name></author><author><name sortKey="Faller, Ll" uniqKey="Faller L">LL Faller</name></author><author><name sortKey="Klitgord, N" uniqKey="Klitgord N">N Klitgord</name></author><author><name sortKey="Mazumdar, V" uniqKey="Mazumdar V">V Mazumdar</name></author><author><name sortKey="Ghodsi, M" uniqKey="Ghodsi M">M Ghodsi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Paster, Bj" uniqKey="Paster B">BJ Paster</name></author><author><name sortKey="Olsen, I" uniqKey="Olsen I">I Olsen</name></author><author><name sortKey="Aas, Ja" uniqKey="Aas J">JA Aas</name></author><author><name sortKey="Dewhirst, Fe" uniqKey="Dewhirst F">FE Dewhirst</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Keijser, Bjf" uniqKey="Keijser B">BJF Keijser</name></author><author><name sortKey="Zaura, E" uniqKey="Zaura E">E Zaura</name></author><author><name sortKey="Huse, Sm" uniqKey="Huse S">SM Huse</name></author><author><name sortKey="Van Der Vossen, Jmbm" uniqKey="Van Der Vossen J">JMBM van der Vossen</name></author><author><name sortKey="Schuren, Fhj" uniqKey="Schuren F">FHJ Schuren</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Abusleme, L" uniqKey="Abusleme L">L Abusleme</name></author><author><name sortKey="Dupuy, Ak" uniqKey="Dupuy A">AK Dupuy</name></author><author><name sortKey="Dutzan, N" uniqKey="Dutzan N">N Dutzan</name></author><author><name sortKey="Silva, N" uniqKey="Silva N">N Silva</name></author><author><name sortKey="Burleson, Ja" uniqKey="Burleson J">JA Burleson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Griffen, Al" uniqKey="Griffen A">AL Griffen</name></author><author><name sortKey="Beall, Cj" uniqKey="Beall C">CJ Beall</name></author><author><name sortKey="Campbell, Jh" uniqKey="Campbell J">JH Campbell</name></author><author><name sortKey="Firestone, Nd" uniqKey="Firestone N">ND Firestone</name></author><author><name sortKey="Kumar, Ps" uniqKey="Kumar P">PS Kumar</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Skrepcinski, Fb" uniqKey="Skrepcinski F">FB Skrepcinski</name></author><author><name sortKey="Niendorff, Wj" uniqKey="Niendorff W">WJ Niendorff</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Badersten, A" uniqKey="Badersten A">A Badersten</name></author><author><name sortKey="Nilveus, R" uniqKey="Nilveus R">R Nilveus</name></author><author><name sortKey="Egelberg, J" uniqKey="Egelberg J">J Egelberg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cobb, Cm" uniqKey="Cobb C">CM Cobb</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fierer, N" uniqKey="Fierer N">N Fierer</name></author><author><name sortKey="Hamady, M" uniqKey="Hamady M">M Hamady</name></author><author><name sortKey="Lauber, Cl" uniqKey="Lauber C">CL Lauber</name></author><author><name sortKey="Knight, R" uniqKey="Knight R">R Knight</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Caporaso, Jg" uniqKey="Caporaso J">JG Caporaso</name></author><author><name sortKey="Kuczynski, J" uniqKey="Kuczynski J">J Kuczynski</name></author><author><name sortKey="Stombaugh, J" uniqKey="Stombaugh J">J Stombaugh</name></author><author><name sortKey="Bittinger, K" uniqKey="Bittinger K">K Bittinger</name></author><author><name sortKey="Bushman, Fd" uniqKey="Bushman F">FD Bushman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Edgar, Rc" uniqKey="Edgar R">RC Edgar</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mcdonald, D" uniqKey="Mcdonald D">D McDonald</name></author><author><name sortKey="Price, Mn" uniqKey="Price M">MN Price</name></author><author><name sortKey="Goodrich, J" uniqKey="Goodrich J">J Goodrich</name></author><author><name sortKey="Nawrocki, Ep" uniqKey="Nawrocki E">EP Nawrocki</name></author><author><name sortKey="Desantis, Tz" uniqKey="Desantis T">TZ DeSantis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wang, Q" uniqKey="Wang Q">Q Wang</name></author><author><name sortKey="Garrity, Gm" uniqKey="Garrity G">GM Garrity</name></author><author><name sortKey="Tiedje, Jm" uniqKey="Tiedje J">JM Tiedje</name></author><author><name sortKey="Cole, Jr" uniqKey="Cole J">JR Cole</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Caporaso, Jg" uniqKey="Caporaso J">JG Caporaso</name></author><author><name sortKey="Bittinger, K" uniqKey="Bittinger K">K Bittinger</name></author><author><name sortKey="Bushman, Fd" uniqKey="Bushman F">FD Bushman</name></author><author><name sortKey="Desantis, Tz" uniqKey="Desantis T">TZ DeSantis</name></author><author><name sortKey="Andersen, Gl" uniqKey="Andersen G">GL Andersen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Price, Mn" uniqKey="Price M">MN Price</name></author><author><name sortKey="Dehal, Ps" uniqKey="Dehal P">PS Dehal</name></author><author><name sortKey="Arkin, Ap" uniqKey="Arkin A">AP Arkin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gower, Jc" uniqKey="Gower J">JC Gower</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Kolenbrander, Pe" uniqKey="Kolenbrander P">PE Kolenbrander</name></author><author><name sortKey="Palmer, Rj" uniqKey="Palmer R">RJ Palmer</name></author><author><name sortKey="Rickard, Ah" uniqKey="Rickard A">AH Rickard</name></author><author><name sortKey="Jakubovics, Ns" uniqKey="Jakubovics N">NS Jakubovics</name></author><author><name sortKey="Chalmers, Ni" uniqKey="Chalmers N">NI Chalmers</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Faith, Jj" uniqKey="Faith J">JJ Faith</name></author><author><name sortKey="Guruge, Jl" uniqKey="Guruge J">JL Guruge</name></author><author><name sortKey="Charbonneau, M" uniqKey="Charbonneau M">M Charbonneau</name></author><author><name sortKey="Subramanian, S" uniqKey="Subramanian S">S Subramanian</name></author><author><name sortKey="Seedorf, H" uniqKey="Seedorf H">H Seedorf</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Slots, J" uniqKey="Slots J">J Slots</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Miller, Ma" uniqKey="Miller M">MA Miller</name></author><author><name sortKey="Pfeiffer, W" uniqKey="Pfeiffer W">W Pfeiffer</name></author><author><name sortKey="Schwartz, T" uniqKey="Schwartz T">T Schwartz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Saber, Mh" uniqKey="Saber M">MH Saber</name></author><author><name sortKey="Schwarzberg, K" uniqKey="Schwarzberg K">K Schwarzberg</name></author><author><name sortKey="Alonaizan, Fa" uniqKey="Alonaizan F">FA Alonaizan</name></author><author><name sortKey="Kelley, St" uniqKey="Kelley S">ST Kelley</name></author><author><name sortKey="Sedghizadeh, Pp" uniqKey="Sedghizadeh P">PP Sedghizadeh</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Italie</li><li>États-Unis</li></country><region><li>Arizona</li><li>Californie</li><li>Illinois</li></region></list><tree><country name="États-Unis"><region name="Californie"><name sortKey="Schwarzberg, Karen" sort="Schwarzberg, Karen" uniqKey="Schwarzberg K" first="Karen" last="Schwarzberg">Karen Schwarzberg</name></region><name sortKey="Alonaizan, Faisal" sort="Alonaizan, Faisal" uniqKey="Alonaizan F" first="Faisal" last="Alonaizan">Faisal Alonaizan</name><name sortKey="Bharti, Balambal" sort="Bharti, Balambal" uniqKey="Bharti B" first="Balambal" last="Bharti">Balambal Bharti</name><name sortKey="Caporaso, J Gregory" sort="Caporaso, J Gregory" uniqKey="Caporaso J" first="J. Gregory" last="Caporaso">J. Gregory Caporaso</name><name sortKey="Caporaso, J Gregory" sort="Caporaso, J Gregory" uniqKey="Caporaso J" first="J. Gregory" last="Caporaso">J. Gregory Caporaso</name><name sortKey="Gottlieb, Roberta A" sort="Gottlieb, Roberta A" uniqKey="Gottlieb R" first="Roberta A." last="Gottlieb">Roberta A. Gottlieb</name><name sortKey="Kelley, Scott T" sort="Kelley, Scott T" uniqKey="Kelley S" first="Scott T." last="Kelley">Scott T. Kelley</name><name sortKey="Le, Rosalin" sort="Le, Rosalin" uniqKey="Le R" first="Rosalin" last="Le">Rosalin Le</name><name sortKey="Lindsay, Suzanne" sort="Lindsay, Suzanne" uniqKey="Lindsay S" first="Suzanne" last="Lindsay">Suzanne Lindsay</name><name sortKey="Saber, Mohamed H" sort="Saber, Mohamed H" uniqKey="Saber M" first="Mohamed H." last="Saber">Mohamed H. Saber</name><name sortKey="Slots, J Rgen" sort="Slots, J Rgen" uniqKey="Slots J" first="J Rgen" last="Slots">J Rgen Slots</name></country><country name="Italie"><noRegion><name sortKey="Casaburi, Giorgio" sort="Casaburi, Giorgio" uniqKey="Casaburi G" first="Giorgio" last="Casaburi">Giorgio Casaburi</name></noRegion><name sortKey="Casaburi, Giorgio" sort="Casaburi, Giorgio" uniqKey="Casaburi G" first="Giorgio" last="Casaburi">Giorgio Casaburi</name><name sortKey="Salvatore, Francesco" sort="Salvatore, Francesco" uniqKey="Salvatore F" first="Francesco" last="Salvatore">Francesco Salvatore</name><name sortKey="Salvatore, Francesco" sort="Salvatore, Francesco" uniqKey="Salvatore F" first="Francesco" last="Salvatore">Francesco Salvatore</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/EdenteV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000342 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000342 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= EdenteV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= PMC:3906071
|texte= The Personal Human Oral Microbiome Obscures the Effects of Treatment on Periodontal Disease
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:24489772" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a EdenteV1
| This area was generated with Dilib version V0.6.33. |  |